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KMID : 0438219760130010101
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Korea University Medical Journal
1976 Volume.13 No. 1 p.101 ~ p.105
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Effect of Mannitol on Sodium and Water Excretion
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Abstract
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During the infusion of 20% mannitol, free water reasorption and osmolar clearance were studied in 15 normal man who were admitted to the department of Intermal Medicine, Woo Sok hospital, College of Medicine, Korea University from January to September, 1975.
The result obtained were as followings.
1. Urine volume was increased by the infusion of mannitol.
2. The amount of excreted sodium and the rate of sodium excretion were increased by the infu-
sion of mannital but none of them were influenced by GFR and the level of serum sodium.
3. Free water reabsorption and osmolar clearance were increased by the infusion of mannitol.
4. The slope of the increment of free water reabsorption and osmolar clearance during mannitol
diuresis was significant.
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KEYWORD
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